Lymphedema: Pathogenesis and Novel Therapies.
Identifieur interne : 000409 ( Main/Exploration ); précédent : 000408; suivant : 000410Lymphedema: Pathogenesis and Novel Therapies.
Auteurs : Joseph H. Dayan ; Catherine L. Ly ; Raghu P. Kataru ; Babak J. MehraraSource :
- Annual review of medicine [ 1545-326X ] ; 2017.
Abstract
Lymphedema affects up to 1 in 6 patients who undergo treatment for a solid tumor in the United States. Its prevalence has increased as more effective oncologic therapies have improved patient survival, but there remains no definitive cure. Recent research has elucidated new details in the pathogenesis of the disease and has demonstrated that it is fundamentally an immunologic progress that ultimately results in inflammation, fibroadipose deposition, impaired lymphangiogenesis, and dysfunctional lymphatic pumping. These findings have allowed for the development of novel medical and surgical therapies that may potentially alter the standard of care for a disease that has largely been treated by compression. This review seeks to provide an overview of the emerging therapies and how they can be utilized for effective management of lymphedema. Expected final online publication date for the Annual Review of Medicine Volume 69 is January 29, 2018. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
DOI: 10.1146/annurev-med-060116-022900
PubMed: 28877002
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000020
- to stream PubMed, to step Curation: 000020
- to stream PubMed, to step Checkpoint: 000020
- to stream Ncbi, to step Merge: 009443
- to stream Ncbi, to step Curation: 009443
- to stream Ncbi, to step Checkpoint: 009443
- to stream Main, to step Merge: 000409
- to stream Main, to step Curation: 000409
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lymphedema: Pathogenesis and Novel Therapies.</title><author><name sortKey="Dayan, Joseph H" sort="Dayan, Joseph H" uniqKey="Dayan J" first="Joseph H" last="Dayan">Joseph H. Dayan</name><affiliation><nlm:affiliation>Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: dayanj@mskcc.org , lyc@mskcc.org , katarur@mskcc.org , mehrarab@mskcc.org.</nlm:affiliation><wicri:noCountry code="subField">mehrarab@mskcc.org.</wicri:noCountry></affiliation></author><author><name sortKey="Ly, Catherine L" sort="Ly, Catherine L" uniqKey="Ly C" first="Catherine L" last="Ly">Catherine L. Ly</name><affiliation><nlm:affiliation>Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: dayanj@mskcc.org , lyc@mskcc.org , katarur@mskcc.org , mehrarab@mskcc.org.</nlm:affiliation><wicri:noCountry code="subField">mehrarab@mskcc.org.</wicri:noCountry></affiliation></author><author><name sortKey="Kataru, Raghu P" sort="Kataru, Raghu P" uniqKey="Kataru R" first="Raghu P" last="Kataru">Raghu P. Kataru</name><affiliation><nlm:affiliation>Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: dayanj@mskcc.org , lyc@mskcc.org , katarur@mskcc.org , mehrarab@mskcc.org.</nlm:affiliation><wicri:noCountry code="subField">mehrarab@mskcc.org.</wicri:noCountry></affiliation></author><author><name sortKey="Mehrara, Babak J" sort="Mehrara, Babak J" uniqKey="Mehrara B" first="Babak J" last="Mehrara">Babak J. Mehrara</name><affiliation><nlm:affiliation>Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: dayanj@mskcc.org , lyc@mskcc.org , katarur@mskcc.org , mehrarab@mskcc.org.</nlm:affiliation><wicri:noCountry code="subField">mehrarab@mskcc.org.</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28877002</idno><idno type="pmid">28877002</idno><idno type="doi">10.1146/annurev-med-060116-022900</idno><idno type="wicri:Area/PubMed/Corpus">000020</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000020</idno><idno type="wicri:Area/PubMed/Curation">000020</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000020</idno><idno type="wicri:Area/PubMed/Checkpoint">000020</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000020</idno><idno type="wicri:Area/Ncbi/Merge">009443</idno><idno type="wicri:Area/Ncbi/Curation">009443</idno><idno type="wicri:Area/Ncbi/Checkpoint">009443</idno><idno type="wicri:Area/Main/Merge">000409</idno><idno type="wicri:Area/Main/Curation">000409</idno><idno type="wicri:Area/Main/Exploration">000409</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Lymphedema: Pathogenesis and Novel Therapies.</title><author><name sortKey="Dayan, Joseph H" sort="Dayan, Joseph H" uniqKey="Dayan J" first="Joseph H" last="Dayan">Joseph H. Dayan</name><affiliation><nlm:affiliation>Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: dayanj@mskcc.org , lyc@mskcc.org , katarur@mskcc.org , mehrarab@mskcc.org.</nlm:affiliation><wicri:noCountry code="subField">mehrarab@mskcc.org.</wicri:noCountry></affiliation></author><author><name sortKey="Ly, Catherine L" sort="Ly, Catherine L" uniqKey="Ly C" first="Catherine L" last="Ly">Catherine L. Ly</name><affiliation><nlm:affiliation>Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: dayanj@mskcc.org , lyc@mskcc.org , katarur@mskcc.org , mehrarab@mskcc.org.</nlm:affiliation><wicri:noCountry code="subField">mehrarab@mskcc.org.</wicri:noCountry></affiliation></author><author><name sortKey="Kataru, Raghu P" sort="Kataru, Raghu P" uniqKey="Kataru R" first="Raghu P" last="Kataru">Raghu P. Kataru</name><affiliation><nlm:affiliation>Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: dayanj@mskcc.org , lyc@mskcc.org , katarur@mskcc.org , mehrarab@mskcc.org.</nlm:affiliation><wicri:noCountry code="subField">mehrarab@mskcc.org.</wicri:noCountry></affiliation></author><author><name sortKey="Mehrara, Babak J" sort="Mehrara, Babak J" uniqKey="Mehrara B" first="Babak J" last="Mehrara">Babak J. Mehrara</name><affiliation><nlm:affiliation>Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: dayanj@mskcc.org , lyc@mskcc.org , katarur@mskcc.org , mehrarab@mskcc.org.</nlm:affiliation><wicri:noCountry code="subField">mehrarab@mskcc.org.</wicri:noCountry></affiliation></author></analytic><series><title level="j">Annual review of medicine</title><idno type="eISSN">1545-326X</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lymphedema affects up to 1 in 6 patients who undergo treatment for a solid tumor in the United States. Its prevalence has increased as more effective oncologic therapies have improved patient survival, but there remains no definitive cure. Recent research has elucidated new details in the pathogenesis of the disease and has demonstrated that it is fundamentally an immunologic progress that ultimately results in inflammation, fibroadipose deposition, impaired lymphangiogenesis, and dysfunctional lymphatic pumping. These findings have allowed for the development of novel medical and surgical therapies that may potentially alter the standard of care for a disease that has largely been treated by compression. This review seeks to provide an overview of the emerging therapies and how they can be utilized for effective management of lymphedema. Expected final online publication date for the Annual Review of Medicine Volume 69 is January 29, 2018. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Dayan, Joseph H" sort="Dayan, Joseph H" uniqKey="Dayan J" first="Joseph H" last="Dayan">Joseph H. Dayan</name><name sortKey="Kataru, Raghu P" sort="Kataru, Raghu P" uniqKey="Kataru R" first="Raghu P" last="Kataru">Raghu P. Kataru</name><name sortKey="Ly, Catherine L" sort="Ly, Catherine L" uniqKey="Ly C" first="Catherine L" last="Ly">Catherine L. Ly</name><name sortKey="Mehrara, Babak J" sort="Mehrara, Babak J" uniqKey="Mehrara B" first="Babak J" last="Mehrara">Babak J. Mehrara</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000409 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000409 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28877002
|texte= Lymphedema: Pathogenesis and Novel Therapies.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28877002" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |